Can I still use the product if it has become frozen after it is originally thawed?
How long can I store the vials in the dry ice shipping container?
With proper dry ice replenishment, the thermal shipping container may be used as temporary storage for up to 30 days from delivery. Please visit the Product Storage & Dry Ice
How is the vaccine stored?
Upon delivery, immediately store frozen multiple dose vaccine vials in an ultra-low-temperature
freezer. A second option is to use your thermal shipping container as temporary storage, if it is consistently replenished with dry ice. Lastly, the vaccine may be stored in the refrigerator at 2°C to 8°C for 120 hours (5 days) but cannot be re-frozen. Please visit the Product Storage & Dry Ice
section for guidelines on maintaining the correct temperature.
At what temperature does the vaccine need to be stored?
Vaccine vials are to be stored in an ultra-low-temperature (ULT) freezer between -80°C and -60°C (-112°F to -76°F), protected from light and kept in the original packaging. The thermal shipping container in which the vaccines arrive can be used as temporary storage. The thermal shipping container maintains a temperature range of ‑90°C to ‑60°C (-130°F to ‑76°F). Storage of the vials between -96°C to -60°C (-141°F to -76°F) is not considered an excursion from the recommended storage condition.
The vaccine may be stored in the refrigerator at 2°C to 8°C for 120 hours (5 days) but cannot be re-frozen.
Do I need to have an ultra-low-temperature freezer to store the vaccine?
If you do not have an ultra-low-temperature
freezer available, you may use the thermal shipping container as temporary storage, if it is consistently replenished with dry ice. Please visit the Product Storage & Dry Ice
section for guidelines on re-icing.
Where can I get an ultra-low-temperature freezer?
Please visit the Product Storage & Dry Ice
section for a list of vendors who offer ultra-low-temperature
freezers for vaccine storage.
Is there preservative in the vaccine?
No, the vaccine does not contain preservative.
How long can I store the vials in the ultra-low-temperature freezer?
Undiluted vaccine vials can be stored in an ultra-low-temperature
freezer until expiration, which is 6 months from the time of manufacturing. Please check the expiration date on the vials and visit the Product Storage & Dry Ice
section for guidelines on storage and handling.
How long can undiluted vials be stored in a refrigerator?
Undiluted vials may be stored in the refrigerator at 2°C to 8°C (35°F to 46°F) for up to 120 hours (5 days) prior to dilution.
Can I still use the product if it has been exposed to light?
During storage, minimize exposure to room light, and avoid exposure to direct sunlight and ultraviolet light. Thawed vials can be handled in room light conditions. If you are a healthcare professional residing in the U.S. and have questions about using the Pfizer-BioNTech
to talk to a Medical Information Specialist or go to https://www.pfizermedicalinformation.com/en-us/pfizer-biontech-covid-19-vaccine
for more information.
How long does it take for frozen vials to thaw?
A full tray of vials will thaw within 3 hours in the refrigerator at 2°C to 8°C (35°F to 46°F). Individual vials will take less time. If needed, a frozen vial may be thawed at room temperature (up to 25°C [77°F]) for 30 minutes.
What should I do if I cannot remove the box with the vial trays?
Please note, the thermal shipping container should not be opened for more than 3 minutes. If you feel resistance when trying to remove the box that holds the vial trays, do not pull it out by force. Keep the box inside the thermal shipping container and remove the vial trays separately using the clear plastic straps.
Are components of the vaccine vial made with latex?
The vial stoppers are not made with natural rubber latex.